Vildagliptin add on therapy in patient with metformin
Reduces festive BG
Reduces Postprandial BG & Glucogen.
No change to 24-hour insulin secretor(U.Cln bnaicrinol Metad 2UU4:89:40/8.84)
Reduces HB1 by 0.6-1.1%
Rapidly absorbed & high bio availability (85%) offer on oral administration
Efficacious, weight neutral with low risk of hyperglycemia as monotherapy
Metformin
Metformin is a Biguanide, lowers blood glucose by increasing the sensitivity of liver, muscle, Fat and other peripheral tissues for uptake of glucose and also enhances effect of insulin.
Metformin reduces the complications of diabetes such as heart disease, retinal damage and kidney disease.